Endocrine Abstracts

Background: Prolonged ingestion of licorice has been known to cause hypokalemia and resistant hypertension amongst other disturbances. This is due to glycyrrhizin that inhibits the 11-β-hydroxysteroid dehydrogenase enzyme type 2 which results into increased plasma cortisol levels that stimulate the mineralocorticoid receptors resulting into apparent mineralocorticoid excess.Case report: A 45-year-old woman resident in an iodine sufficient area, heav...

Carcinoid cardiac disease is a rare cause of intrinsic right heart valve disease with significant impact on mortality. We present the case of a young male patient (38 yrs old) complaining in the last 5 yrs of abdominal pain associated with flushing of the face that progressively worsened (up to 15 episodes/day) accompanied by diarrhoea and, in the last 2 months, by night sweats, distension of the abdomen, bilateral ankle swelling and progressive limitation in effort. Endocrine...

BackgroundAcromegaly is a rare disease, caused by an autonomous excessive secretion of growth hormone (GH). Apart from skeletal alterations, the GH excess leads to metabolic and visceral disease. Thus, one of the most frequent associated complications is the cardio-vascular one represented by hypertension, cardiomyopathy and ischemic heart disease. The presence of multiple complications in patients with acromegaly leads not only to increased morbidity an...

IntroductionOver time, different substances and protocols have been used and tested for stimulating calcitonin (CT). Some of them proved to be useful in diagnosing medullary thyroid carcinoma (MTC). However, these are associated with side-effects, with various duration, intensity and severity.ObjectiveTo report the side-effects observed during CT stimulation test with calcium (Ca) gluconate.<p class="abst...

Background: Subacute thyroiditis, autoimmune thyroiditis and an atypical form of thyroiditis due to primary injury of the thyroid gland by SARS Cov2 itself are complications of COVID-19. Angiotensin-converting enzyme 2 is also expressed in the thyroid gland. On the other hand, both untreated thyrotoxicosis and COVID-19 affects heart, generating cardiac complications.Case report: A 36-year-old woman resident in an iodine sufficient area, heavy smoker, pre...

Background: Dopamine agonists (DAs) were associated with valvular dysfunction in patients with Parkinson’s disease due to their fibrotic effect through the serotoninergic receptor. It is more difficult to prove the same effects in patients with prolactinoma due to the lower doses, variable doses and the longer follow-up period. Aim: To assess echocardiographic features in patients with prolactinoma under DA treatment.Methods: ...

Background: Vitamin D deficiency is the most common nutritional deficiency, estimated to affect almost one billion people worldwide. Multiple factors influence 25(OH)D levels: nutrition, sunlight exposure, outdoor physical activity, skin color. Patients with active acromegaly (AA) have lower 25(OH)D levels compared with healthy population and are at a higher risk to develop vitamin D deficiency. Also, some studies have suggested a possible protective role of vitamin D on the c...